Overview
Avalon Pharmaceuticals is a biopharmaceutical company focused on the discovery, development and
commercialization of first-in-class cancer therapeutics. Our lead product candidate,
AVN944,
an IMPDH inhibitor, is in Phase II clinical development. Late stage preclinical programs include inhibitors of the
Beta-catenin and
PLK3 (Aurora/Centrosome)
pathways, and
discovery programs for inhibitors of the
Survivin and
Myc
pathways. We have partnerships with
Merck,
AstraZeneca/MedImmune,
ChemDiv,
Medarex,
and
Novartis which utilize our proprietary drug discovery and development platform, AvalonRx
®. AvalonRx
® is based on large-scale biomarker identification and monitoring to discover and develop therapeutics for pathways that have historically been characterized as "undruggable."
Avalon Pharmaceuticals was established in 1999 and completed its initial public
offering in 2005. The company is headquartered in Germantown, Maryland.